Assisted Hatching is another modern technique that can increase the chances of fertility in an IVF treatment. In order for the successful implantation of the embryo in the uterus it has to hatch out of its zonal pellucida which is a layer of protein surrounding the embryo. Now it has been found that embryos with thin shells can easily attach to the uterine lining. . So when there has been failed IVF it be could because of the thick shell that prevents the eggs from attaching. In such cases hatching can be helpful as it creates a small hole on the outer shell of the embryo. This is done carefully only on the outer shell and without harming the embryo inside. Once this is completed the embryo will easily be able to come out of its zonal pellucida and attach to the uterus.
When is this recommended?
This is procedure is looked into when there is one or more IVF failure.
When the women is above 35 years of age.
Embryos with thick outer shell.
There is high level day 3 follicle stimulating hormone (FSH), or they show a low AMH level or low antral follicle count.
Hatching is done after the eggs are procured and it has been fertilized in the laboratory. The embryo is held with a specialized equipment sort of like a pippette. Using a hollow needle a solution is poured over the outer shell of embryo.
The acidic solution dilutes the outer shell.
Next the embryo will be washed and placed back in the incubator.
Now it is ready to be placed in the uterus of the mother and the process will be completed.